Benefits of taking Probotic Complete
Probiotics is the term used to describe bacteria supplements that are taken to improve gut health. The most commonly taken bacteria are Lactobacillus acidophilus and bifidobacterium, of which there are numerous strains of each. There are several hypotheses for why supplemental probiotics may work to enhance the health of the gut. Normalizing the composition of intestinal bacteria is most obvious, which can lead to healthy changes in the gut immune system, such as a reduction in the secretion of inflammatory mediators in the gut. Probiotics seem to help the gut immune system eliminate antigens (proteins that can cause inflammation and disease). It is thought that probiotics can reduce excessive permeability of the gut, which will eliminate the absorption of such inflammatory antigens (1). More to the point, probiotics were shown to reinforce the different lines of gut defense, which are immune exclusion, immune elimination, and immune regulation (2).
Gut (digestive system) health is, in part, dependent upon the presence of a healthy bacterial flora, as it is called. In short, we have literally trillions of bacteria in our digestive tract, which number close to the total number of cells that make up the human body.
Research has demonstrated that significant structural changes occur in the gut bacterial flora with aging, and this was especially evident with respect to bifidobacteria, which are considered to be protective. It is proposed that reductions in these organisms in the large intestine may be related to increased disease risk in the elderly. Researchers endeavored to measure the levels of bifidobacteria in the stool of elderly subjects and found that, indeed, levels were reduced. Remarkably, however, was the fact that one individual highly skewed the results. This subject was described as an unusually healthy and fitness conscious 67 year old male, who had very high counts of these organisms (3).
Researchers recently treated patients suffering with irritable bowel syndrome with probiotics, and found that there was a symptomatic improvement (4,5). In some studies with pregnant and then nursing mothers, supplementation with probiotics led to reduced expression of allergic diseases in their infants (6,7).
Based on the above, it seems reasonable to supplement the gut with probiotics. The best way to do this is not known for sure. We can either supplement on a continuous basis, or cycle our supplementation over the year. I have done both.
References
1. Isolauri E. Probiotics: effects on immunity. Am J Clin Nutr 2001; 73(suppl):444S-50S
2. Isolauri E. Probiotics in human disease. Am J Clin Nutr 2001; 73(6):1142S-1146S
3. Hopkins MJ et al. Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16s rRNA abundance, and community cellular fatty acid profiles. Gut 2001; 48:198-205
4. Fan YJ, Chen SJ, Yu YC, Si JM, Kiu B. A probiotic treatment containing Lactobacillus, Bifidobacterium and Enterococcus improves IBS symptoms in an open label trial. J Zhejiang Univ Sci B. 2006; 7(12):987-91
5. Colecchia A, Vestito A, La Rocca A, Pasqui F, Nikiforaki A, Festi D. Effect of a symbiotic preparation on the clinical manifestations of irritable bowel syndrome, constipation-variant. Results of an open, uncontrolled multicenter study. Minerva Gastroenterol Dietol. 2006; 52(4):349-58
6. Kalliomaki M, Salminen S, Arvilommi H, Kero P, Koskinen P, Isolauri E. Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial. Lancet. 2001; 357(9262):1076-79
7. Rautava S, Kalliomaki M, Isolauri E. Probiotics during pregnancy and breast-feeding might confer immunomodulatory protection against atopic disease in the infant. J Allergy Clin Immunol. 2002; 109(1):119-21